Aricept Evess Adverse Reactions

The most common adverse events are diarrhoea, muscle cramps, fatigue, nausea, vomiting and insomnia.
Adverse reactions reported as more than an isolated case are listed as follows, arranged by system organ class and by frequency. Frequencies are defined as: Very common (≥1/10), common (≥1/100, <1/10), uncommon (≥1/1000, <1/100), rare (≥1/10,000, <1/1000), very rare (<1/10,000) and not known (cannot be estimated from available data).
Infections and Infestations: Common: Common cold.
Metabolism and Nutrition Disorders: Common: Anorexia.
Psychiatric Disorders: Common: Hallucinations**, agitation**, aggressive behaviour**.
Nervous System Disorders: Common: Syncope*, dizziness, insomnia. Uncommon: Seizure*. Rare: Extrapyramidal symptoms.
Cardiac Disorders: Uncommon: Bradycardia. Rare: Sino-atrial block, atrioventricular block.
Gastrointestinal Disorders: Very Common: Diarrhoea, nausea. Common: Vomiting, abdominal disturbance. Uncommon: Gastrointestinal haemorrhage, gastric ulcer and duodenal ulcers.
Hepatobiliary Disorders: Rare: Liver dysfunction including hepatitis (in cases of unexplained liver dysfunction, withdrawal of Aricept Evess should be considered).
Skin and Subcutaneous Tissue Disorders: Common: Rash, pruritus.
Musculoskeletal, Connective Tissue and Bone Disorders: Common: Muscle cramps.
Renal and Urinary Disorders: Common: Urinary incontinence.
General Disorders and Administration Site Conditions: Very Common: Headache. Common: Fatigue, pain.
Investigations: Uncommon: Minor increase in serum concentration of muscle creatine kinase.
Injury and Poisoning: Common: Accident.
*In investigating patients for syncope or seizure, the possibility of heart block or long sinusal pauses should be considered (see Precautions).
**Reports of hallucinations, agitation and aggressive behaviour have resolved on dose-reduction or discontinuation of treatment.